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O siringofibroadenoma écrino (SFAE) é um tumor benigno raro que se origina das glândulas sudoríparas écrinas. Apresenta predileção pelas extremidades de indivíduos idosos e pode surgir em associação com várias doenças adquiridas ou hereditárias e com afecções cutâneas neoplásicas. Relatamos caso de homem de 48 anos, tetraplégico por mielite transversa há 30 anos, com tumoração plantar rapidamente progressiva de difícil diagnóstico
Eccrine syringofibroadenoma (EFAS) is a rare benign tumor that originates from the eccrine sweat glands. It has a predilection for the extremities of elderly individuals and may arise in association with various acquired or hereditary pathologies and neoplastic skin disorders. We report the case of a 48-year-old man who had been quadriplegic due to transverse myelitis for 30 years, with a rapidly progressive plantar tumor that was difficult to diagnose.
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Abstract Eccrine poroma is the term that includes benign neoplasms of the terminal duct of the eccrine sweat glands, which may clinically and dermoscopically resemble other melanoma and non-melanoma skin tumors. They are often located on the extremities (especially palms and soles), presenting as normochromic or erythematous papules and nodules, measuring up to 2 cm. Pigmented variants are uncommon, accounting for less than 20% of cases. This report describes a 37-year-old man who developed a large pigmented eccrine poroma on his right shoulder, causing diagnostic difficulty. Histopathological examination revealed a nodular neoplasm consisting of small, monomorphic, cuboidal cells, with ample, eosinophilic cytoplasm and well-defined borders, in addition to conspicuous intercellular bridges, with melanin deposits diffusely distributed inside them. The absence of cytological atypia, cellular pleomorphism, increased mitotic activity, and necrosis foci corroborated the diagnostic exclusion of porocarcinoma, which can develop from eccrine poroma.
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Malignant eccrine poroma is a rare malignancy of eccrine glands , whose diagnosis is an index of high suspicion and challenging to a clinician. A case of 67 year old female with swelling over left cheek since 20 years with no radiation exposure and no comorbidities , was investigated and wide local excision with 5mm margins from the tumor was performed , and specimen sent for biopsy - which revealed tumor cells arranged in lobules with peripheral palisading , ductal and squamous differentiation - suggestive of Porocarcinoma.Wide surgical excision is the mainstay of treatment, resulting in cure rates of 70–80% when the margins are clear. Some studies also reported good outcomes with Mohs micrographic surgery, and this technique could also be considered 1. Other treatments such as chemotherapy and radiotherapy have also been reported in the literature without clear standard guidelines
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Introdução: O poroma écrino é uma lesão benigna geralmente solitária e nodular, sendo frequente na palma da mão e planta do pé. Devido à sua raridade, a variante pigmentada pode facilmente ser confundida com melanoma. Relata-se caso clínico de poroma écrino pigmentado no couro cabeludo, localização considerada atípica, simulando melanoma maligno. Relato de Caso: Paciente do sexo masculino, 73 anos, fototipo IV, referia aparecimento de lesão indolor no couro cabeludo há 6 meses, associada a sangramentos esporádicos. Ao exame, apresentava-se como nódulo enegrecido com centro eritematoso, de consistência firme, medindo aproximadamente 1,5 cm de diâmetro. A dermatoscopia observou padrão vascular predominante em glóbulos. A principal hipótese diagnóstica foi de melanoma, porém o estudo histopatológico concluiu poroma écrino parcialmente pigmentado. Discussão: O porome écrino pigmentado é um tumor raro com fisiopatologia desconhecida. É considerado como um grande simulador por mimetizar clinicamente diversos tumores, benignos e malignos. Neste caso clínico, após o exame dermatológico e avaliação dermatoscópica, a principal hipótese diagnóstica era de melanoma maligno. Os poucos casos clínicos publicados com estudo dermatoscópico apresentaram história semelhante e dúvida diagnóstica, tendo sido esclarecido o diagnóstico somente após a avaliação histopatológica. Conclusão: É importante que a avaliação de lesões de pele pigmentadas seja feita tanto clinicamente quanto com dermatoscopia, usada como ferramenta que corrobora com o diagnóstico. A hipótese diagnóstica de poroma écrino deve ser considerada nos casos em que as lesões pigmentadas não tenham características melanocíticas, sendo o diagnóstico confirmado apenas após avaliação histopatológica.
Introduction: The eccrine poroma is a benign lesion, usually solitary and nodular, frequent in the palm and foot plant. Due to its rarity, the pigmented variant can easily be confused with melanoma. A clinical case of pigmented poroma on the scalp is reported; this is a location considered atypical, simulating malignant melanoma. Case Report: A 73-year-old male patient, phototype IV, reported the appearance of a painless lesion on the scalp for six months, associated with sporadic bleeding. On examination, it presented as a blackened nodule with an erythematous center of firm consistency, measuring approximately 1.5 cm in diameter. Dermatoscopy observed a predominant vascular pattern in blood cells. The main diagnostic hypothesis was melanoma, but the histopathological study concluded partially pigmented eccrine poroma. Discussion: Pigmented eccrine poroma is a rare tumor with unknown pathophysiology. It is considered a great simulator for clinically imitate several tumors, benign and malignant. In this clinical case, after dermatological examination and dermoscopic evaluation, the main diagnostic hypothesis was malignant melanoma. The few clinical cases published with a dermatoscopic study presented a similar history and diagnostic doubt, and the diagnosis was clarified only after histopathological evaluation. Conclusion: The evaluation of pigmented skin lesions must be done both clinically and with dermatoscopy, used as a tool that corroborates the diagnosis. The diagnostic hypothesis of eccrine poroma should be considered when pigmented lesions do not have melanocytic characteristics, and the diagnosis is confirmed only after histopathological evaluation.
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Abstract The Borst-Jadassohn phenomenon is a morphological finding that consists of the presence of well-defined nests of cells located in the spiny stratum of an acanthotic epidermis. One of the neoplasms where this phenomenon is found is hidroacanthoma simplex. This neoplasm is considered the intraepidermal form of the eccrine poroma. Despite its benign nature, malignant transformations are reported. The present article reports a case of hidroacanthoma simplex and discusses the dermoscopy of this phenomenon.
Subject(s)
Humans , Female , Aged, 80 and over , Skin Neoplasms/pathology , Skin Neoplasms/diagnostic imaging , Acanthoma/pathology , Acanthoma/diagnostic imaging , Biopsy , Dermoscopy/methods , Epidermis/pathology , Epidermis/diagnostic imagingABSTRACT
Atypical Fibroxanthoma is an unusual dermal mesenchymal tumor. It especially affects older adults and occurs in areas of sun exposure. We report a 75 years old male with a history of sun exposure without using a hat presenting with a scalp nodule. An incisional biopsy showed an atypical fibroxantoma. In a new surgical procedure, the tumor was completely excised. The tumor relapsed in two occasions after subsequent excisions and the patient was treated with adjuvant radiotherapy avoiding new relapses.
Subject(s)
Humans , Male , Aged , Scalp/pathology , Skin Neoplasms/pathology , Xanthomatosis/pathology , Skin Neoplasms/radiotherapy , Biopsy , Xanthomatosis/radiotherapy , Treatment OutcomeABSTRACT
Abstract Eccrine porocarcinoma (EPC) is a rare malignant skin tumor. The dermoscopy of invasive EPC reveals focal presence of whitish-pink, structureless areas surrounded by pinkish-white halos. In an eccrine poroma (EP), such areas present diffuse distribution in the "frog- eggs" pattern. We reported an EPC in situ that presents a transitional dermoscopy pattern between EP and invasive EPC. We found a diffuse distribution; whitish-pink, structureless areas surrounded by pinkish-white halos; a central exulceration and a polymorphic vascular pattern.
Subject(s)
Humans , Female , Aged , Sweat Gland Neoplasms/diagnostic imaging , Poroma/diagnostic imaging , Eccrine Porocarcinoma/diagnostic imaging , Sweat Gland Neoplasms/pathology , Biopsy , Dermoscopy/methods , Diagnosis, Differential , Poroma/pathology , Eccrine Porocarcinoma/pathology , LegABSTRACT
Background: Troublesome tumors (Skin adnexal tumors (SAT)) pose a major diagnostic difficulties because of their wide spectrum and variants, their rarity, differentiation along two or more adnexal lines and their complicated nomenclature to both the surgeon and the pathologist. Histopathology is the gold standard of diagnosis with immunohistochemistry playing a limited role.Materials and methods: A Prospective study of skin adnexal tumors (n =25) diagnosed on histopathological examination over a period of 2 years (June 2015 to May 2017). All slides were stained with H & E.Results: Majority of the patients are in the third and fourth decade. Females outnumbered the males.Twenty-two tumors are benign and 3 are malignant. Most common skin adnexal tumors are Hair follicle origin tumors comprising of 15cases (60%). In that most common benign tumor is Trichoepithelioma. Head and neck region is the commonest site involved.Conclusion: Skin adnexal tumors are relatively rare. Benign adnexal tumors are more common than the malignant lesions. Histopathology is essential to confirm the diagnosis.
ABSTRACT
El poroma es un tumor benigno infrecuente derivado de la porción intraepitelial del epitelio ductal de la glándula sudorípara. La presentación clínica más habitual es un pápula o nódulo de color rosado a rojo, de pequeño diámetro, localizado con mayor frecuencia en palmas y plantas, generalmente asintomático. Debido a su variabilidad morfológica, los poromas son usualmente difíciles de reconocer, siendo la dermatoscopía una herramienta útil en su diagnóstico. Presentamos el caso de un paciente masculino con un gran tumor en su pierna derecha de 40 mm de diámetro, con características dermatoscópicas compatibles con poroma no pigmentado. El diagnóstico confirmatorio se realizó con una biopsia incisional seguido de la extirpación quirúrgica completa del tumor
Poroma is a rare benign tumour derived from the intraepithelial portion of the sweat glands' ductal epithelium. The most common clinical presentation is a pink to red papule or nodule, small in diameter, predominantly in the palms and soles and generally asymptomatic. Due to its morphologic variability, poromas are usually difficult to recognize, thus dermatoscopy becomes a useful aid in its diagnosis. We present the case of a male patient with a large tumour on his right leg, 40 mm in diameter, with dermatoscopic features consistent with nonpigmented poroma. Confirmatory diagnosis was made by incisional biopsy followed by the total surgical excision of the tumor.
Subject(s)
Humans , Male , Middle Aged , Sweat Gland Neoplasms/diagnosis , Dermoscopy/methods , Poroma/diagnosis , Sweat Gland Neoplasms/pathology , Diagnosis, Differential , Poroma/pathologyABSTRACT
Abstract: Poroid neoplasms are benign epithelial proliferations with eccrine sweat gland differentiation. They are a challenging diagnosis because of the clinical heterogeneity, being able to mimic several malignant neoplasms. They are classified into classic poroma, hidroacanthoma simplex, dermal duct tumor and poroid hidradenoma. Association of histological subtypes occurs in more than 25% of cases. We report a case of a combined poroid neoplasia of classical poroma and poroid hidradenoma, reviewing its dermatoscopic features.
Subject(s)
Humans , Female , Aged , Sweat Gland Neoplasms/pathology , Sweat Gland Neoplasms/diagnostic imaging , Poroma/pathology , Poroma/diagnostic imaging , DermoscopyABSTRACT
Eccrine poroma is a benign solitary tumor with acrosyringeal differentiation that usually occurs on the sole or either side of the foot. Rapid growth of eccrine poroma during pregnancy has rarely been reported. We demonstrate a unique case of a 37-year-old pregnant woman who suffered from enlarged eccrine poroma on her left palm, which was tiny for 10 years but suddenly grew to a size of bean-sized reddish brown colored, pedunculated mass during pregnancy. The patient denied a previous history of trauma or infection to the lesion. Histopathologic findings with a shave biopsy were consistent with eccrine poroma. After the tumor was completely removed by the shave biopsy, no recurrence was noted for 5 months.
Subject(s)
Adult , Female , Humans , Pregnancy , Biopsy , Eccrine Glands , Foot , Poroma , Pregnant Women , RecurrenceABSTRACT
Los poromas ecrinos son tumores anexiales benignos que se originan de la porción intraepidérmica del conducto de la glándula sudorípara. Representan aproximadamente 10 % de todos los tumores de estas glándulas. La variante clásica de poroma se caracteriza por una neoformación de aspecto papular de color piel o eritematosa, con predilección por las palmas y plantas. Sin embargo, estos tumores en términos clínicos pueden exhibir características polimórficas que puedan hacer difícil su diagnóstico. En estos casos, la dermatoscopia es una herramienta inmediata y útil que puede apoyar el mismo. El estudio histopatológico es necesario para la conclusión definitiva. Suele diagnosticarse entre la quinta y séptima décadas de la vida. Por tales razones se presenta el caso de un paciente de 30 años de edad en el que se diagnosticó poroma ecrino en una lesión palmar.
Eccrine poromas are benign adnexal tumors which originate from the intraepidermal duct portion of the sweat gland. They represent approximately 10% of all tumors of these glands. The classical variant of poroma is characterized by a neoformation of papular aspect of skin color or erythematous, with a predilection for palms and soles. However, these tumors in clinical terms may exhibit polymorphic characteristics that may make diagnosis difficult. In these cases, dermatoscopy is an immediate and useful tool that can support it. The histopathological study is necessary for the definitive conclusion. It is usually diagnosed between the fifth and seventh decades of life. For these reasons the case of a 30-year-old patient diagnosed with eccrine poroma in a palmar lesion is presented.
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Abstract: Eccrine poromas and porocarcinomas are adnexal tumors derived from the sweat duct epithelium. However, eccrine poroma is benign in nature, whilst eccrine porocarcinoma is regarded as its malignant counterpart. We report the case of a man who presented simultaneously with an eccrine poroma and eccrine porocarcinoma. Both lesions had no clear distinctive features, enhancing the need of high-level clinical suspicion together with surgical excision and histopathology for prompt diagnosis confirmation.
Subject(s)
Humans , Male , Aged , Sweat Gland Neoplasms/pathology , Poroma/pathology , Eccrine Porocarcinoma/pathology , Neoplasms, Multiple Primary/pathology , Sweat Gland Neoplasms/diagnosis , Biopsy , Diagnosis, Differential , Poroma/diagnosis , Eccrine Porocarcinoma/diagnosis , Neoplasms, Multiple Primary/diagnosisABSTRACT
Resumen:El porocarcinoma ecrino es un tipo muy poco frecuente de cáncer de piel, originado en la porción epidérmica de las glándulas sudoríparas ecrinas. Representa no más del 0.01% de los tumores cutáneos. El 20% de los porocarcinomas ecrinos son recurrentes y el 20% producen metástasis a ganglios linfáticos. Se ha reportado escasos casos de metástasis a distancia. Tiene un índice de mortalidad del 67% de los pacientes con metástasis.El diagnóstico es basado en los hallazgos histopatológicos y los estudios complementarios de inmunohistoquímica, a veces necesarios para el diagnóstico diferencial con otros tipos más frecuentes de cáncer de piel.No existen pruebas de que este tipo de carcinoma responda a la quimioterapia ni la radioterapia. Se considera que el manejo principal debe ser la resección quirúrgica y la electroquimioterapia.
Abstract:Eccrine porocarcinoma is a rare type of skin cáncer arising from the intraepidermal portion of eccrine sweat glands, representing no more tan 0.01% of all cutaneous tumors. 20% of the Eccrine porocarcinoma will recur and 20% will metastasize to regional lymph nodes. Few cases of distant metastases has been reported . There is a mortality rate of 67% in patients with metastases. The diagnosis is primarily based on histopathologic findings and complementary immunohistochemistry for differential diagnosis mainly with more frequent skin cáncer.Neither chemotherapy nor radiation therapy has been proven to be of clinical benefit in treating this type of carcinoma. It is considered that the management should be based on surgical resection and electrochemotherapy.
Subject(s)
Humans , Sweat Gland Neoplasms , Sweat Glands , Poroma , Eccrine PorocarcinomaABSTRACT
Abstract: Acrospiroma, also known as hidradenoma, is a rare cutaneous tumor that has several histological characteristics. As a consequence, a high index of suspicion is necessary for its diagnosis. Here we report a case that illustrates the importance of a good clinical-pathologic correlation in order to recognize this disease.
Subject(s)
Humans , Male , Adult , Scalp/pathology , Skin Neoplasms/pathology , Sweat Gland Neoplasms/pathology , Acrospiroma/pathology , Head and Neck Neoplasms/pathology , DermoscopyABSTRACT
Abstract: Hidroacanthoma simplex is a rare intraepidermal neoplasia that arises from the acrosyringial portion of the eccrine duct. Malignant transformation of hidroacanthoma simplex is reported in the literature and the treatment is performed with wide excision or Mohs micrographic surgery. We report the first case successfully treated with cryosurgery with a long-term follow up.